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Prkaa1

WebPRKAA1 gene codes for the catalytic alpha 1 subunit of the AMP-activated protein kinase which is an important cellular metabolic stress regulator. It might assist tumor cells … WebJun 2, 2024 · The 5′-AMP-activated protein kinase (AMPK), encoded by AMP-activated protein kinase catalytic subunit alpha-1 gene (PRKAA1), plays a pivotal role in carcinogenesis, owing to its involvement in cell growth, cell cycle modulation, rapamycin-pathway restriction, and energy metabolism. 6-8 PRKAA1 gene is located at 5p13.1.

5562 - Gene ResultPRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 [ (human)]

WebFeb 27, 2024 · Graphical representation of PRKAA1 and PRKAA2 genomic DNA sequences.PRKAA1 and PRKAA2 encompass 9 and 10 exons, respectively. Exons are figured as vertical black rectangles.PRKAA1 exon 7 is highlighted in red.Intronic regions are depicted by connecting roof-shaped lines. 3′ untranslated regions (3′UTR) are indicated. WebNov 7, 2024 · Increased expression of Prkaa1/AMPK in atheroprone ECs. To assess the functional role of endothelial Prkaa1 in atherosclerosis, we first examined the levels of … sandy beach litchfield ct https://alexeykaretnikov.com

Reactome p-T183-Prkaa1 [cytosol]

5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this gene belongs to the serine/threonine protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. Th… WebPRKAA1 silencing inhibited cell growth, colony formation, and glycolysis but enhanced apoptosis, while the PRKAA1 overexpression promoted cell growth, colony formation, … WebApr 11, 2024 · Prkaa1-T172D fl/fl phospho-mutant knock-in mice were generated by GemPharmatech (Nanjing, China) from embryonic stem cells (ESCs) modified via homologous recombination. To express phospho-mutant AMPKα1 specifically in MSCs, we crossed Prkaa1-T172D fl/fl mice with Prx1-Cre mice to generate conditionally AMPKα1 … sandy beach lodge

PRKAA1/AMPKα1-driven glycolysis in endothelial cells

Category:AMPK alpha 1/PRKAA1 Protein Overview: Sequence

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Prkaa1

Reactome p-T183-Prkaa1 [cytosol]

Web人抗核周因子(APF)抗体ELISA试剂盒 ；英文名称： Human anti-perinuclear factor(APF)antibody ELISA Kit ；实验名称： 人抗核周因子(APF)抗体ELISA试剂盒 ；实验别名： 人抗核周因子(APF)抗体ELISA试剂盒 48T/96T ；规格： 48T/96T 报价 人抗核周因子(APF)抗体ELISA试剂盒实验目的：本试剂盒仅供研究使用 ，用于 用于测定血清 ... WebApr 4, 2024 · PRKAA1 could combine with miR-497-5p, and LINC00473 knockdown or miR-497-5p overexpression downregulated the mRNA and protein expression of PRKAA1. …

Prkaa1

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WebThe PRKAA1 protein expression in GC tissues and corresponding non-tumor gastric tissues measured by IHC analysis was consistent with western blot assay that PRKAA1 was … WebJul 28, 2009 · AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or …

Web本发明公开了一类以环内过氧桥键倍半萜为母核的化合物在代谢相关脂肪性肝病中的用途。该以环内过氧桥键倍半萜为母核的化合物具有如式I中的结构；其中，A为＝O，‑OH，‑OCH3，‑OCH2CH3或者‑OC4H5O3；该以环内过氧桥键倍半萜为母核的化合物用于制备治疗代谢相关脂肪性肝病的药物或组合物。本 ... Web108079 Ensembl ENSG00000162409 ENSMUSG00000028518 UniProt P54646 Q8BRK8 RefSeq (mRNA) NM_006252 NM_178143 NM_001356568 RefSeq (protein) NP_006243 NP_835279 NP_001343497 Location (UCSC) Chr 1: 56.65 – 56.72 Mb Chr 4: 104.89 – 104.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 5'-AMP …

WebExpression and activity of the AMP-activated protein kinase (AMPK) α1 catalytic subunit of the heterotrimeric kinase significantly correlates with poor outcome for colorectal cancer patients.Hence there is considerable interest in uncovering signalling vulnerabilities arising from this oncogenic elevation of AMPKα1 signalling.We have therefore attenuated … WebMar 21, 2024 · PRKAA1 (Protein Kinase AMP-Activated Catalytic Subunit Alpha 1) is a Protein Coding gene. Diseases associated with PRKAA1 include Wolff-Parkinson-White …

WebPrkaa1, Ampk1 Chain chain:1-559 Reference Genes BioGPS Gene:65248 Prkaa1. ENSEMBL:ENSRNOG00000012799 Prkaa1. KEGG ...

WebPRKAA1 is also named as AMPK1, ACACA kinase, HMGCR kinase. It is a mammalian homologue of sucrose non-fermenting protein kinase (SNF-1), which belongs to a serine/threonine protein kinase family. It has 2 isoforms with molecular mass of 63-66 kDa produced by alternative splicing.10929-2-AP can recognize both AMPK Alpha 1 and … short bowel syndrome risk factorsWebJan 12, 2024 · We studied recruitment and viability of Prkaa1-deficient myeloid cells in mice and the phenotype of these mice in the context of cardio-metabolic diseases. We found … short bowel syndrome statpearlsWebPRKAA1 INFORMATION. Proteini. Full gene name according to HGNC. Protein kinase AMP-activated catalytic subunit alpha 1. Gene namei. Official gene symbol, which is … short bowel syndrome mntWebOct 9, 2015 · Variant rs13361707 is located in the first intron of PRKAA1 at 5p13.1, which was primarily found to be associated with NCGC risk by a GWAS in a Chinese population(1006 non-cardia gastric cancer ... short bowel syndrome in dogsWebMar 21, 2024 · AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 … short bowel syndrome steatorrheaWebJun 7, 2024 · The mammalian 5-prime-AMP-activated protein kinase (AMPK) appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is a heterotrimeric protein composed of 1 alpha subunit (e.g., PRKAA1), 1 beta subunit (e.g., PRKAB1; 602740 ), and 1 gamma subunit … shortbow hypixel skyblockWebprkaa1. Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within negative regulation of hh target transcription factor activity. Predicted to be part of … shortbow knee pads drop rate